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About the product

What type of drug is Lipoless?

Lipoless is an injectable medication for weekly use, indicated for people with obesity or type 2 diabetes. It contains tirzepatide, a dual GIP/GLP-1 agonist that acts on metabolism, appetite and blood glucose.

It is a drug approved by DINAVISA that can only be used under medical prescription. It is not a supplement and cannot be purchased without prescription.

Lipoless is available in six doses (2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg and 15 mg) and comes in prefilled syringe, vials and disposable single-dose prefilled auto-injectors.

Yes. It should be stored between 2°C and 8°C, never freeze. 

Yes, it is an innovation developed by Laboratorios Eticos Paraguay, with international quality standards and active ingredients approved by the FDA and the EMA.

Lipoless is developed and distributed by Ethical Laboratories Paraguaya national company with more than 40 years of experience, focused on providing innovative health solutions with international support.

About its use

What makes it different from other weight-loss drugs?

Unlike other treatments, Lipoless acts on two regulatory hormones instead of just one. This dual action improves insulin sensitivity, prolongs satiety and enhances clinical weight loss. 

Lipoless is applied subcutaneously in the abdominal area. It is for weekly use and is designed to facilitate self-administration.

 The first results can be seen between 2 and 4 weeks, depending on the organism and habits of each person.

For Obesity and Overweight: An effective treatment that helps to lose weight in a safe and lasting way, acting on the causes of overweight by reducing hunger and increasing the feeling of satiety.

For Diabetes Mellitus Type 2: Helps to better control blood sugar, lowering long-term glucose levels (HbA1c) and with low risk of low blood sugar.


For Cardiovascular Disease (CVD): It helps to take care of the heart, improving blood pressure and cholesterol, especially in people with higher cardiovascular risk.

For Metabolic Syndrome (several combined health problems such as overweight, high blood pressure and high blood sugar): It acts on several problems at the same time, such as abdominal fat, insulin resistance, high cholesterol and high blood pressure.

 For liver fat (not caused by alcohol): The weight loss produced by the treatment also helps to improve liver health, reducing inflammation and liver damage.

Ease in following the treatment of chronic diseases: It is applied only once a week, which makes it easier to follow the treatment in the long term.

If it has been 4 days or less since the day you were supposed to give your injection: Give the missed dose as soon as you remember. Then continue with your regular weekly application day.
If more than 4 days have passed: Skip the missed dose completely and wait for your next scheduled dose. Do not apply two doses together to make up for the missed dose.

Oral Contraceptives: Tirzepide can delay stomach emptying, which could theoretically affect the absorption of birth control pills. It is recommended to use a barrier method (such as a condom) or a non-oral method during the first 4 weeks after starting treatment and after each dose increase.

Alcohol: There is no direct contraindication, but it should be consumed in moderation. Alcohol can increase the risk of hypoglycemia (low blood sugar), especially if combined with other diabetes medications. It can also irritate the stomach, worsening side effects such as nausea.

Lipoless tirzepatide is absolutely contraindicated in the following cases:

  • History of Medullary Thyroid Cancer
  • Neoplasia Syndrome
  • Multiple Endocrine Type Hypersensitivity or Severe Allergy
  • Pancreatitis
  • Severe gastrointestinal disease
  • Pregnancy and lactation
  • Use with other diabetes medications
  • Kidney problems
  • Gallbladder disease
  • Diabetic retinopathy

It is vital to remember that this list is not exhaustive and that only a healthcare professional can determine whether tirzepatide is a safe and appropriate treatment for your specific situation, weighing the benefits against the potential risks.

 Yes, although it is recommended to accompany it with good habits to enhance the results.

 Yes, when stopping treatment, a significant portion of the lost weight is regained. Rather than a mysterious "rebound effect", it is the logical consequence of stopping treatment for a chronic disease such as obesity.

Treatment with tirzepatide may be associated with certain risks that are important to know before initiating therapy. Although it is an advanced and effective therapeutic tool for the management of overweight, obesity and type II diabetes, its use should always be supervised by a health professional.

Important Warnings

  • In animal studies, thyroid tumors, including medullary thyroid carcinoma, have been observed. Although this risk has not been confirmed in humans, tirzepatide should not be used in people with a personal or family history of this type of cancer, or in those with Multiple Endocrine Neoplasia type 2 syndrome (MEN 2).
  • It should not be used in people with known allergy to tirzepatide or to any of the components of its formula.

Serious adverse effects

  • Acute pancreatitisIf you experience severe and persistent abdominal pain, with or without vomiting, it is recommended to stop treatment and consult immediately.
  • HypoglycemiaThe risk of low blood glucose levels increases if tirzepatide is combined with other drugs such as insulin or sulfonylureas. May manifest as sweating, tremors, blurred vision, palpitations or confusion.
  • Severe allergic reactionsIn rare cases, facial swelling, difficulty breathing, hives or severe dizziness may occur. They require urgent medical attention.
  • Dehydration and renal complicationsProlonged vomiting or diarrhea can cause fluid loss. Maintaining good hydration is key.
  • Severe gastrointestinal disordersThe following symptoms may occur: intense nausea, delayed gastric emptying or persistent abdominal pain.
  • Vesicular complicationsas gallstones. In case of pain in the upper abdomen, fever or jaundice, consultation is recommended.
  • Changes in visionespecially in people with diabetes.
  • Caution in surgical proceduresif you are about to undergo surgery with general anesthesia, inform in advance that you are using tirzepatide, as it could affect gastric emptying and increase the risk of aspiration.

Common side effects

  • Nausea, vomiting, loss of appetite, constipation, indigestion and abdominal discomfort are frequent reactions, especially at the beginning of treatment. They usually diminish with time.

Special considerations

Before starting treatment, inform your doctor if:

  • You are pregnant or plan to be pregnant.
  • You use oral contraceptives (another temporary method may be recommended).
  • You suffer from gastrointestinal diseases such as gastroparesis.
  • You have diabetic retinopathy or other chronic conditions.
  • You are taking other medications or supplements.

This summary does not replace medical consultation. In case of any doubt or unexpected symptom, consult your trusted health professional.